A panel of medical experts overseeing the Bush administration's smallpox
immunization campaign advised yesterday against expanding the effort to millions
of emergency response workers, saying a series of unexpected heart complications
raises concerns about the safety of the vaccine.
The recommendation by the Advisory Committee on Immunization Practices comes
as many state and federal health officials say privately that the program is at
a standstill, falling far short of President Bush's desire to vaccinate
millions. At its meeting in Atlanta yesterday, the advisory panel approved a
one-page resolution saying it would be "unwise to expand beyond its current,
pre-event smallpox vaccination recommendations" and begin inoculating first
responders "because of the new and unanticipated safety concerns."
Joseph Henderson, the chief bioterrorism official at the Centers for Disease
Control and Prevention, said the agency is conducting a six-month assessment of
its smallpox preparedness efforts and expects to suggest adjustments to the
White House with more focus on education and training, emergency response drills
and faster reporting of suspicious outbreaks.
Investing almost solely in vaccinations "is not a practical approach right
now," Henderson said in an interview. Nevertheless, he said, CDC is "committed
to the president's decision" and intends to press for more volunteers to be
immunized.
In a news briefing, CDC Director Julie L. Gerberding said the administration
will review the panel's recommendation but is likely to encourage more people to
be immunized.
"The more people we have vaccinated, the better off we'll be, and the fact
that we have almost 40,000 people vaccinated is I think a tremendous step
forward compared to where we were just six months ago," she said. "So we've made
enormous progress, but we have more to do."
When Bush announced in December his plan to resume smallpox vaccinations, his
health advisers outlined an ambitious timetable for inoculating nearly 500,000
health care workers in early 2003 and as many as 10 million medical and
emergency response personnel by summer. So far, fewer than 40,000 people have
been immunized.
Skepticism about the true threat of a biological attack, partisan wrangling
over a compensation package for people harmed by the vaccine and public health
crises such as the outbreak of severe acute respiratory syndrome dampened
participation in the program, Henderson said.
States' participation has varied -- 34 people in Rhode Island have been
immunized, compared with more than 3,700 in Florida, according to the June 13
CDC report. The District has immunized about 105, Virginia 867 and Maryland 735,
according to the CDC.
From the outset, health experts knew -- and worried -- about complications
from the smallpox vaccine, made from a live virus called vaccinia. But what
startled the medical community were the few dozen cardiac cases, in particular
some heart attacks and several cases of swelling in or around the heart.
The first hints of heart complications came in the military, which immunized
more than 450,000 personnel before the war in Iraq. At least 27 military
employees and 21 civilian workers suffered heart inflammation after being
vaccinated, prompting the administration to tighten its screening procedures.
The panel and other medical experts have urged more extensive studies on the
possible link between the vaccine and heart trouble before continuing the
program.
Although smallpox was believed to be eradicated in the late 1970s, many
experts fear terrorist groups or hostile nations such as Iraq may have acquired
the germ and could use it as a weapon. There is no treatment for the highly
contagious illness, but vaccination given within several days of exposure often
protects people from the virus.
Last year, the advisory committee urged a small-scale, cautious approach to
resuming smallpox vaccinations after 30 years. But for the first time in
history, the administration overrode those recommendations and unveiled its plan
for inoculating millions.
Several groups that have voiced skepticism about the original policy
yesterday applauded the panel's cautionary note.
"The lesson for the future is that public officials can't ignore the voice of
health care workers on the front lines when they make decisions that affect them
and their patients," said Andrew L. Stern, president of the Service Employees
International Union. As the nation's largest health care union, SEIU led the
fight for compensation of injured workers.