Looking for a Vaccine to Defang the Lyme Tick

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http://query.nytimes.com/gst/abstract.html?res=F10B1EFB385A0C738EDDAC0894DB404482

Health & Fitness | May 20, 2003, Tuesday
Looking for a Vaccine to Defang the Lyme Tick

By JAMES GORMAN (NYT) 2144 words
Late Edition - Final , Section F , Page 1 , Column 5

LEAD PARAGRAPH - Dr. José Ribeiro is sequencing the ''spitome'' of the deer tick. This is a little bit like sequencing a genome, except that it has to do with saliva, specifically the saliva of the deer tick, the tiny menace that lives off deer and white-footed mice and likes to give suburban gardeners Lyme disease.

What Dr. Ribeiro and other scientists at the National Institute of Allergy and Infectious Diseases in Bethesda, Md., are finding is that tick spit is a complex weapon, with an array of components that alleviate pain, keep blood from coagulating and subdue the host's immune system at the site of the bite. ''Tick saliva is amazing,'' said Dr. Fred S. Kantor of the Yale School of Medicine, who is also working on deciphering tick saliva.



 

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