US Advisors Back Wyeth Vaccine for Ear Infections

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Anyone out there wondering if vaccines haven't caused this entire problem in the first place? How many ear infections did children get prior to smallpox, prior to DPT vaccine?  And what role does breastfeeding play in preventing ear infections? - SM

http://story.news.yahoo.com/news?tmpl=story&u=/nm/20020521/sc_nm/health_wyeth_prevnar_dc_2

US Advisors Back Wyeth Vaccine for Ear Infections
Tue May 21, 2:58 PM ET

SILVER SPRING, Md. (Reuters) - A U.S. advisory panel on Tuesday recommended approval of Wyeth's Prevnar pneumonia vaccine for preventing some ear infections in children.

 

   

Prevnar hit the U.S. market in 2000 for combating seven strains of bacteria that cause pneumonia.

Already given routinely to U.S. infants, winning Food and Drug Administration (news - web sites) approval for ear infections would allow Wyeth to promote Prevnar for the common childhood malady.

The FDA usually follows the advice of its advisory panels.

Ear infections are common in U.S. children, occurring in more than 60 percent in their first year of life and about 90 percent by age 5. Pneumococcus is the bacteria most often reported as responsible for ear infections, but they also can be caused by other bacteria or viruses.

The advisors voted 13-3 to recommend Prevnar for ear infections, despite concern by some panel members that the drug has limited effectiveness.

In one study, Prevnar showed a 57 percent reduction in episodes of ear infections caused by the seven strains of pneumococcus the vaccine targets but reduced ear infections from any cause by only six percent.

"We're not talking about huge efficacy rates here," said panel member Gary Overturf, from the University of New Mexico School of Medicine.

But Michael Decker, a committee member and scientist at Aventis SA unit Aventis Pasteur, said limited efficacy was better than none. "If you turn down every partial solution, you never have a solution," he said.

Wyeth estimates Prevnar could eliminate 1 million to 1.5 million doctor visits a year and cut ear-tube placements, a treatment for recurrent ear infections, by 60,000 a year.

Shares of Wyeth fell $1.12, or 1.9 percent, to $27.12, in afternoon trade on the New York Stock Exchange (news - web sites).

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